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Humboldt-Universität zu Berlin - Mathematisch-Naturwissen­schaft­liche Fakultät - Kardiovaskuläre Physik

Humboldt-Universität zu Berlin | Mathematisch-Naturwissen­schaft­liche Fakultät | Institut für Physik | Kardiovaskuläre Physik | Publications | Correlation dimension analysis of heart rate variability in patients with dilated cardiomyopathy

R Carvajal, N Wessel, M Vallverdu, P Caminal, and A Voss (2005)

Correlation dimension analysis of heart rate variability in patients with dilated cardiomyopathy

Comput Methods Programs Biomed, 78:133–140.

A correlation dimension analysis of heart rate variability (HRV) was applied to a group of 55 patients with dilated cardiomyopathy (DCM) and 55 healthy subjects as controls. The 24-h RR time series for each subject was divided into segments of 10,000 beats to determine the correlation dimension (CD) per segment. A study of the influence of the time delay (lag) in the calculation of CD was performed. Good discrimination between both groups (p<0.005) was obtained with lag values of 5 or greater. CD values of DCM patients (8.4+/-1.9) were significantly lower than CD values for controls (9.5+/-1.9). An analysis of CD values of HRV showed that for healthy people, CD night values (10.6+/-1.8) were significant greater than CD day values (9.2+/-1.9), revealing a circadian rhythm. In DCM patients, this circadian rhythm was lost and there were no differences between CD values in day (8.8+/-2.4) and night (8.9+/-2.1).

[DOI:http://dx.doi.org/10.1016/j.cmpb.2005.01.00410.1016/j.cmpb.2005.01.004] [PubMed:http://www.ncbi.nlm.nih.gov/pubmed/1584826815848268]