Humboldt-Universität zu Berlin - Mathematisch-Naturwissen­schaft­liche Fakultät - Photobiophysik

Publikationen

2025

I. Maaßen, A. Luther, M. Varzandeh, S. Hackbarth, D. Waberski
Photodynamic Inactivation of Bacteria in Boar Semen with Blue LED Light
DOI: https://doi.org/10.3390/microorganisms13030643

2024

A. Luther, M Varzendeh, C. Beckermann, L. Freyer, I. Maaßes, H. Odenhof, S. Hackbarth, D. Waberski
Fertility after photodynamic inactivation of bacteria in extended boar semen
DOI: https://doi.org/10.3389/fmicb.2024.1429749

2023

M. Tavares, R. Islam, V. Šubr, S. Hackbarth, S. Gao, K. Yang, V. Lobaz, J. Fang, T. Etrych
Polymer theranostics with multiple stimuli-based activation of photodynamic therapy and tumor imaging
DOI: https://doi.org/10.7150/thno.86211

S. Hackbarth, S. Gao, V. Šubr, L. Lin, J. Pohl, T. Etrych and J. Fang
Singlet Oxygen In Vivo: It Is All about Intensity—Part 2
DOI: https://doi.org/10.3390/jpm13050781

2022

S. Hackbarth, R. Islam, V. Šubr, T. Etrych and J. Fang
Singlet Oxygen In Vivo: It Is All about Intensity
DOI: https://doi.org/10.3390/jpm12060891

2020

S. Hackbarth, M. Pfitzner, J. Pohl, B. Röder
Singlet Oxygen Detection and Imaging
DOI: https://doi.org/10.1007/978-3-031-02391-0

2019

V. Trümper, A. von Knethen, A. Preuß, E. Ermilov, S. Hackbarth, L. Kuchler, S. Gunne, A. Schäfer, T. Bornhütter, G. Vereb, L. Ujlaky-Nagy, B. Brüne, B. Röder, M. Schindler , M. J. Parnham, T. Knape
Flow cytometry-based FRET identifies binding intensities in PPARγ1 protein-protein interactions in living cells
DOI:  10.7150/thno.29367

S. Hackbarth, W. Islam, J. Fang, V. Šubr, B. Röder, T. Etrych, H. Maeda
Singlet oxygen phosphorescence detection in vivo identifies PDT-induced anoxia in solid tumors
DOI: 10.1039/c8pp00570b

J. Fang, V. Šubrb, W. Islam, S. Hackbarth, R. Islam, T. Etrych, K. Ulbrich, H. Maeda
N-(2-hydroxypropyl)methacrylamide polymer conjugated pyropheophorbide-a, a promising tumor-targeted theranostic probe for photodynamic therapy and imaging
DOI: https://doi.org/10.1016/j.ejpb.2018.06.005

I. O.L. Bacellar, R. M. Cordeiro, P. Mahling, M. S. Baptista, B.Röder, S. Hackbarth
Oxygen distribution in the fluid/gel phases of lipid membranes
DOI: https://doi.org/10.1016/j.bbamem.2019.01.019

2018

S. Pfitzner, J. C. Schlothauer, B. Röder, S. Hackbarth
Time- and spectrally resolved singlet oxygen phosphorescence detection—discriminating disturbance signals
DOI: https://doi.org/10.1088/1555-6611/aac5cc

S. Hackbarth, S. Pfitzner, L. Guo, J. Ge, P. Wang, B. Röder
Singlet Oxygen Kinetics in Polymeric Photosensitizers
DOI: http://dx.doi.org/10.1021/acs.jpcc.8b02052

2017

L. Guo, J. Ge, Q. Liu, Q. Jia, H. Zhang, W. Liu, G. Niu, S. Liu, J. Gong, S. Hackbarth, P. Wang
Versatile Polymer Nanoparticles as Two-Photon-Triggered Photosensitizers for Simultaneous Cellular, Deep-Tissue Imaging, and Photodynamic Therapy
DOI: https://dx.doi.org/10.1002/adhm.201601431

2016

S. Hackbarth, B. Röder
Singlet oxygen luminescence kinetics in heterogeneous environment – Identification of the photosensitizer localization in small unilamellar vesicles Supplementary information
DOI: 

M. Pfitzner, J. C. Schlothauer, E. Bastien, S. Hackbarth, L. Bezdetnaya, H. Lassalle, B. Röder
Prospects of in vivo singlet oxygen luminescence monitoring: Kinetics at different locations on living mice
DOI: https://dx.doi.org/10.1016/j.pdpt.2016.03.002

S. Hackbarth, T. Bornhütter, B. Röder
Singlet Oxygen in Heterogeneous Systems
DOI: https://dx.doi.org/10.1039/9781782626992-FP001

S. Hackbarth
Photosensitizer activity imaging on he microscopic scale
DOI: ?

2015

S. B. Lohan, S. Bauersachs, S. Ahlberg, N. Baisaeng, C. M. Keck, R. H. Müller, E. Witte, K. Wolk, S. Hackbarth, B. Röder, J. Lademann, M. C. Meinke
Ultra-small lipid nanoparticles promote the penetration of coenzyme Q10 in skin cells and counteract oxidative stress
DOI: http://dx.doi.org/10.1016/j.ejpb.2014.12.008

S. Hackbarth, B. Röder
Singlet oxygen luminescence kinetics in a heterogeneous environment – identification of the photosensitizer localization in small unilamellar vesicles
DOI: https://dx.doi.org/10.1039/c4pp00229f

E. Bastien, R. Schneider, S. Hackbarth, D. Dumas, J. Jasniewski, B. Röder, L. Bezdetnaya and
H. Lassalle
PAMAM G4.5-chlorin e6 dendrimeric nanoparticles for enhanced photodynamic effects
DOI: https://dx.doi.org/10.1039/c5pp00274e

2014

F. Rancan, B. Nazemi, S. Rautenberg, M. Ryll, S. Hadam, Q. Gao, S. Hackbarth, S. F. Haag, C. Graf, E. Rühl, U. Blume-Peytavi, J. Lademann, A. Vogt and M. C. Meinke
Ultraviolet radiation and nanoparticle induced intracellular free radicals generation measured in human keratinocytes by electron paramagnetic resonance spectroscopy
DOI: https://dx.doi.org/10.1111/srt.12104

 

J. C. J. M. D. S. Menezes, M. A. F. Faustino, K. T. de Oliveira, M. P. Uliana, V. F. Ferreira, S. Hackbarth, B. Röder, T. T. Tasso, T. Furuyama, N. Kobayashi, A. M. S. Silva, M. G. P. M. S. Neves, J. A. S. Cavaleiro
Synthesis of New Chlorin e6 Trimethyl and Protoporphyrin IX Dimethyl Ester Derivatives and Their hotophysical and Electrochemical Characterizations
DOI: https://dx.doi.org/10.1002/chem.201403214

2013

S. Wieczorek, E. Krause, S. Hackbarth, B. Röder, A. K. H. Hirsch, H. G. Börner
Exploiting Specific Interactions toward Next-Generation Polymeric
Drug Transporters
DOI: https://dx.doi.org/10.1021/ja311895z

J. C. Schlothauer, J. Falckenhayn, T. Perna, S. Hackbarth, B. Röder
Luminescence investigation of photosensitizer distribution in skin: correlation of singlet oxygen kinetics with the microarchitecture of the epidermis
DOI: https://dx.doi.org/10.1117/1.JBO.18.11.115001

F. Rancan, S. Amselgruber, S. Hadam, S. Munier, V. Pavot, B. Verrier, S. Hackbarth, B. Combadiere, U. Blume-Peytavi, A. Vogt
Particle-based transcutaneous administration of HIV-1 p24 protein to human skin explants and targeting of epidermal antigen presenting cells
DOI: https://dx.doi.org/10.1016/j.jconrel.2013.12.022

A. Preuß, L. Zeugner, S. Hackbarth, M.A.F. Faustino, M.G.P.M.S. Neves, J.A.S. Cavaleiro, B. Roeder
Photoinactivation of Escherichia coli (SURE2) without intracellular uptake of the photosensitizer
DOI: https://dx.doi.org/10.1111/jam.12018

M. Q. Mesquita, J. C. J. M. D. S. Menezes, M. G. P. M. S. Neves, A. C. Tomé, J. A. S. Cavaleiro, Â. Cunha, A. Almeida, S. Hackbarth, B. Röder, M. A. F. Faustino
Photodynamic inactivation of bioluminescent Escherichia coli by neutral and cationic pyrrolidine-fused chlorins and isobacteriochlorins
DOI: http://dx.doi.org/10.1016/j.bmcl.2013.12.097

S. P. Lopes, J. C. J. M. D. S. Menezes, S. Hackbarth, D. C. G. A. Pinto, M. A. F. Faustino, A. M. S. Silva, M. G. P. M. S. Neves, B. Röder, J. A. S. Cavaleiro
New flavonoid–porphyrin conjugates via Buchwald–Hartwig amination: synthesis and photophysical studies
DOI: http://dx.doi.org/10.1016/j.tetlet.2013.07.089

K. Hestroffer, R. Braun, A. Ugur, J. W. Tomm, S. Hackbarth, B. Röder, F. Hatami
Surface InP/In 0.48Ga 0.52P quantum dots: Carrier recombination dynamics and their interaction with fluorescent dyes
DOI: http://dx.doi.org/10.1063/1.4827188

2013 Hackbarth

S. Hackbarth, J. Schlothauer, A. Preuss, B. Röder
Highly sensitive time resolved singlet oxygen luminescence detection using LEDs as the excitation source
DOI: http://dx.doi.org/10.1088/1612-2011/10/12/125702

2012

J. C. Schlothauer, S. Hackbarth, L. Jäger, K. Drobniewski, H. Patel, S. M. Gorun, B. Röder
Time-resolved singlet oxygen luminescence detection under photodynamic therapy relevant conditions: comparison of ex vivo application of two photosensitizer formulations
DOI: http://dx.doi.org/10.1117/1.JBO.17.11.115005

F. Rancan, Q. Gao, C. Graf, S. Troppens, S. Hadam, S. Hackbarth, C. Kembuan, U. Blume-Peytavi, E. Rühl, J. Lademann, A. Vogt 
Skin Penetration and Cellular Uptake of Amorphous Silica Nanoparticles with Variable Size, Surface  Functionalization, and Colloidal Stability
DOI: https://dx.doi.org/10.1021/nn301622h

N. M.M. Moura, M. A.F. Faustino, M.G.P.M.S. Neves, A. C. Tome, E. M. Rakib, A. Hannioui, S. Mojahidi, S. Hackbarth, B. Röder, F. A. Almeida Paz, A. M.S. Silva, J. A.S. Cavaleiro
Novel pyrazoline and pyrazole porphyrin derivatives: synthesis and photophysical properties
DOI: https://dx.doi.org/10.1016/j.tet.2012.07.072

S. Hackbarth, J. Schlothauer, A. Preuß, C. Ludwig, B. Röder
Time resolved sub-cellular singlet oxygen detection – ensemble measurements versus single cell experiments
DOI: https://dx.doi.org/10.7452/lapl.201110146

S. V. Bhosale, S. Hackbarth, S. J. Langford, S. V. Bhosale
Light-Induced Electron Transfer over Distances of 5, 10, and 15 Š within Water-Filled Yoctowells
DOI: https://dx.doi.org/0.1002/asia.201100533

2011

A. Preuß, K. Chen, S. Hackbarth, M. Wacker, K. Langer, B. Röder
Photosensitizer loaded HSA nanoparticles II: In vitro investigations
DOI: https://dx.doi.org/10.1016/j.ijpharm.2010.11.023

T. Maisch, S. Hackbarth, J. Regensburger, A. Felgenträger, W. Bäumler, M. Landthaler, B. Röde
Photodynamic inactivation of multi-resistant bacteria (PIB) – a new approach to treat superficial infections in the 21 st century
DOI: https://dx.doi.org/10.1111/j.1610-0387.2010.07577.x

2010

J. Schlothauer, B. Röder, S. Hackbarth, J. Lademann
In vivo detection of time-resolved singlet oxygen luminescence under PDT relevant conditions
DOI: ?

A. Preuß, S. Hackbarth, M. Wacker, T. Knobloch, K. Langer, B. Röder
Comprehensive in vitro investigations on biodegradable photosensitizer-nanoparticle delivery systems
DOI: http://dx.doi.org/10.1016/j.jconrel.2010.07.089

S. Hackbarth, J. Schlothauer, A. Preuß, B. Röde
New insights to primary photodynamic effects – Singlet oxygen kinetics in living cells
DOI: http://dx.doi.org/10.1016/j.jphotobiol.2009.11.013

K. Chen, M. Wacker, S. Hackbarth, C. Ludwig, K. Langer, B. Röder 
Photophysical evaluation of mTHPC-loaded HSA nanoparticles as novel PDT delivery systems
DOI: http://dx.doi.org/10.1016/j.jphotobiol.2010.08.006

2009

J. Schlothauer, S. Hackbarth, B. Röder
A new benchmark for time-resolved detection of singlet oxygen luminescence – revealing the evolution of lifetime in living cells with low dose illumination
DOI: https://dx.doi.org/10.1002/lapl.200810116

F. Rancan, D. Papakostas, S. Hadam, S. Hackbarth, T. Delair, C. Primard, B. Verrier, W. Sterry, U. Blume-Peytavi, A. Vogt 
Investigation of Polylactic Acid (PLA) Nanoparticles as Drug Delivery Systems for Local Dermatotherapy
DOI: https://dx.doi.org/0.1007/s11095-009-9919-x

S. Hackbarth, J. Schlothauer, A. Preuß, B. Röder
Singlet oxygen kinetics inside living cells: observation of endogenous quencher consumption and consequences for the spatial resolution in time-resolved measurements
DOI: ?